Prediction of Basic and Instrumental ADLs in MCI and Dementia: An Exploratory
Study. 
   Lead Investigator:    Scott Mooney
   Institution      :    Central Arkansas VA Healthcare System
   E-Mail           :    Scott.Mooney@va.gov
   Proposal ID      :    1442



   Proposal Description:
   1) Grand goal for this research is to elucidate which, if any, biologic (e.g.,  imaging results, past medical and psychiatric histories, family medical           history), elements from neurological exam, subjective cognitive difficulties,     neurocognitive test results or components, and/or psychologic data captured in   the NACC UDS v3 that may demonstrate utility in the prediction of spared/not     spared basic and instrumental ADL status as measured by the Functional Activity  Questionnaire.                                                                   Such research may aid in the development of algorithms that can be further       tested/replicated prospectively to aid clinicians in identification of a         interventional target or need in terms of disposition planning and support for   basic and instrumental ADL functioning. An understudied area.                     Such research may also serve to enhance appreciation of the ecological validity  of medical factors, neurocognitive, neurobehavioral, and psychiatric assessment  approaches in the prediction of ADLs in persons with MCI and presumed dementia.  2) The research will test the hypothesis that medical factors, neurocognitive,   neurobehavioral, and psychiatric assessment approaches predict impaired basic     and instrumental ADLs status in persons with presumed dementia.